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GENE - TERM ANNOTATION REPORT

RGD ID: 631332
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tph2
Name: tryptophan hydroxylase 2
Acc ID: DOID:0050741
Term: alcohol dependence
Definition: A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Alcohol_dependence "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tph2 ISOTPH2 (Homo sapiens)597621681RGDDNA:SNP, haplotypes: :multiple 
Tph2no_associationISOTPH2 (Homo sapiens)597621693RGDassociated with alcohol dependence;DNA:SNPs, haplotypes: :multiple 
Tph2no_associationISOTPH2 (Homo sapiens)597830065RGDDNA:SNP:promoter:-703G>T 
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