Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	628758
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Ptk2b
Name:	protein tyrosine kinase 2 beta

Acc ID:	CHEBI:41774
Term:	tamoxifen
Definition:	A stilbenoid that has formula 371.51460.
Chemical ID:	MESH:D013629

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Ptk2b	decreases expression	ISO	PTK2B (Homo sapiens)	6480464	CTD	Tamoxifen results in decreased expression of PTK2B mRNA	PMID:15590111

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.