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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628719
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp4x1
Name: cytochrome P450, family 4, subfamily x, polypeptide 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp4x1affects expressionISOCyp4x1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of CYP4X1 mRNAPMID:21570461
Cyp4x1decreases expressionISOCYP4X1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CYP4X1 mRNAPMID:20106945 PMID:26159488
Cyp4x1increases expressionISOCyp4x1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of CYP4X1 mRNAPMID:28213091
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