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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a23-3a1
Name: cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
Acc ID: CHEBI:3441
Term: carvedilol
Definition: A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure.
Chemical ID: MESH:C043211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a23-3a1increases metabolic processingEXP 6480464CTDCYP3A23-3A1 protein results in increased metabolism of CarvedilolPMID:29415952
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