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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62389
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Klf6
Name: KLF transcription factor 6
Acc ID: CHEBI:52289
Term: wortmannin
Definition: A delta-lactone that has formula C23H24O8.
Chemical ID: MESH:C009687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klf6decreases expressionISOKLF6 (Homo sapiens)6480464CTDWortmannin results in decreased expression of KLF6 mRNAPMID:22486562
Klf6multiple interactionsISOKLF6 (Homo sapiens)6480464CTDWortmannin inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Wortmannin inhibits the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]PMID:22486562
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