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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621872
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mt-co2
Name: mitochondrially encoded cytochrome c oxidase II
Acc ID: CHEBI:63718
Term: tenofovir disoproxil fumarate
Definition: A fumarate salt prepared from equimolar amounts of tenofovir disoproxil and fumaric acid. It is used in combination therapy for the treatment of HIV infection.
Chemical ID: MESH:D000068698
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt-co2multiple interactionsISOMT-CO2 (Homo sapiens)6480464CTDTenofovir promotes the reaction [Didanosine results in decreased expression of COX2 mRNA]PMID:16940060
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