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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccn5
Name: cellular communication network factor 5
Acc ID: CHEBI:18388
Term: apigenin
Definition: A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7. It induces autophagy in leukaemia cells.
Chemical ID: MESH:D047310
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccn5increases expressionISOCCN5 (Homo sapiens)6480464CTDApigenin results in increased expression of CCN5 mRNAPMID:23384675
Ccn5multiple interactionsISOCCN5 (Homo sapiens)6480464CTDESR1 protein inhibits the reaction [Apigenin results in increased expression of CCN5 mRNA]PMID:23384675
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