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GENE - TERM ANNOTATION REPORT

RGD ID: 621759
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vwf
Name: von Willebrand factor
Acc ID: GO:0007596
Term: blood coagulation
Definition: The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
Definition Source(s): PMID:30700128
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vwfacts_upstream_of_or_withinISOVwf (Mus musculus)1624291RGDMGI:2153009 PMID:17380206 PMID:21037087 PMID:9689113

PMID:17380206 PMID:21037087 PMID:9689113
Vwfinvolved_inISOVWF (Homo sapiens)1624291RGD PMID:16409464

PMID:16409464
Vwfinvolved_inIEAUniProtKB-KW:KW-00941600115UniProtGO_REF:0000043

GO_REF:0000043
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