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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621737
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Flt4
Name: Fms related receptor tyrosine kinase 4
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Flt4decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of FLT4 mRNAPMID:34747641
Flt4increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of FLT4 mRNAPMID:33387578
Flt4multiple interactionsISOFlt4 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of FLT4 mRNAPMID:15251184
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