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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621699
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a7
Name: solute carrier family 22 member 7
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a7decreases expressionEXP 6480464CTDPhenobarbital results in decreased expression of SLC22A7 mRNAPMID:17381134
Slc22a7decreases expressionISOSLC22A7 (Homo sapiens)6480464CTDPhenobarbital results in decreased expression of SLC22A7 mRNAPMID:16837569
Slc22a7decreases expressionISOSlc22a7 (Mus musculus)6480464CTDPhenobarbital results in decreased expression of SLC22A7 mRNAPMID:19482888 PMID:19850644
Slc22a7multiple interactionsISOSlc22a7 (Mus musculus)6480464CTDNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SLC22A7 mRNA]; NR1I3 protein promotes the reaction [Phenobarbital results in decreased expression of SLC22A7 mRNA]PMID:19482888 PMID:19850644
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