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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621699
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a7
Name: solute carrier family 22 member 7
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a7affects expressionISOSlc22a7 (Mus musculus)6480464CTDAcetaminophen affects the expression of SLC22A7 mRNAPMID:17562736
Slc22a7decreases activityISOSLC22A7 (Homo sapiens)6480464CTDAcetaminophen results in decreased activity of SLC22A7 proteinPMID:12388633
Slc22a7decreases expressionISOSLC22A7 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of SLC22A7 mRNAPMID:21420995 PMID:29067470
Slc22a7multiple interactionsISOSLC22A7 (Homo sapiens)6480464CTDAcetaminophen inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]PMID:15901346
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