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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621658
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sec16b
Name: SEC16 homolog B, endoplasmic reticulum export factor
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sec16bdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SEC16B mRNAPMID:30816183
Sec16bincreases expressionEXP 6480464CTDbisphenol A results in increased expression of SEC16B mRNAPMID:25181051
Sec16baffects splicingISOSec16b (Mus musculus)6480464CTDbisphenol A affects the splicing of SEC16B mRNAPMID:37894381
Sec16bdecreases expressionISOSec16b (Mus musculus)6480464CTDbisphenol A results in decreased expression of SEC16B mRNAPMID:32156529
Sec16bdecreases methylationISOSEC16B (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of SEC16B genePMID:31601247
Sec16bmultiple interactionsISOSEC16B (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SEC16B mRNAPMID:28628672
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