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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Per3
Name: period circadian regulator 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Per3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PER3 mRNAPMID:25181051 PMID:30816183 PMID:32145629
Per3increases methylationEXP 6480464CTDbisphenol A results in increased methylation of PER3 genePMID:28505145
Per3decreases expressionISOPer3 (Mus musculus)6480464CTDbisphenol A results in decreased expression of PER3 mRNAPMID:32156529
Per3multiple interactionsISOPer3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of PER3 mRNAPMID:28433925
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