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GENE - TERM ANNOTATION REPORT

RGD ID: 62151
Species: Mus musculus
RGD Object: Gene
Symbol: Gabra5
Name: gamma-aminobutyric acid type A receptor subunit alpha 5
Acc ID: GO:0051932
Term: synaptic transmission, GABAergic
Definition: The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Definition Source(s): GOC:dos, ISBN:0126603030
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabra5involved_inIBAPANTHER:PTN000436343 or UniProtKB:P14867 or UniProtKB:P18507 or Gabra1 (Rattus norvegicus) or Gabrg2 (Rattus norvegicus) or Gabra6 (Rattus norvegicus)2290270GO_Central GO_REF:0000033
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