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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621509
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ctsb
Name: cathepsin B
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ctsbincreases expressionISOCtsb (Mus musculus)6480464CTDGlucose results in increased expression of CTSB mRNAPMID:17178593
Ctsbmultiple interactionsISOCTSB (Homo sapiens)6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CTSB protein; Melatonin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CTSB protein]PMID:21392095
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