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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621506
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk8
Name: mitogen-activated protein kinase 8
Acc ID: CHEBI:31206
Term: ammonium chloride
Definition: An inorganic chloride having ammonium as the counterion.
Chemical ID: MESH:D000643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk8affects expressionEXP 6480464CTDAmmonium Chloride affects the expression of MAPK8 mRNAPMID:16483693
Mapk8increases phosphorylationEXP 6480464CTDAmmonium Chloride results in increased phosphorylation of MAPK8 proteinPMID:30508503
Mapk8multiple interactionsEXP 6480464CTDTLR5 gene mutant form inhibits the reaction [Ammonium Chloride results in increased phosphorylation of MAPK8 protein]PMID:30508503
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