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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621414
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnh2
Name: potassium voltage-gated channel subfamily H member 2
Acc ID: CHEBI:6456
Term: lidocaine
Definition: The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Chemical ID: MESH:D008012
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnh2decreases activityISOKCNH2 (Homo sapiens)6480464CTDLidocaine results in decreased activity of KCNH2 proteinPMID:24052561
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