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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621400
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Acc ID: CHEBI:34215
Term: 2,3',5-trichlorobiphenyl
Definition: A trichlorobiphenyl that is 1,4-dichlorobenzene in which one of the hydrogens has been replaced by a 3-chlorophenyl group.
Chemical ID: MESH:C091160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i3increases activityISONR1I3 (Homo sapiens)6480464CTD2,5,3'-trichlorobiphenyl analog results in increased activity of NR1I3 protein; 2,5,3'-trichlorobiphenyl results in increased activity of NR1I3 proteinPMID:26231822
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