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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621375
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ikbkb
Name: inhibitor of nuclear factor kappa B kinase subunit beta
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ikbkbincreases expressionISOIKBKB (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of IKBKB mRNAPMID:23452621
Ikbkbmultiple interactionsISOIKBKB (Homo sapiens)6480464CTD3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA]; Genistein inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA]; Plant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA]; resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA]PMID:23452621
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