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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621363
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpc2
Name: glypican 2
Acc ID: CHEBI:32234
Term: titanium dioxide
Definition: A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.
Chemical ID: MESH:C009495
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpc2decreases expressionISOGpc2 (Mus musculus)6480464CTDtitanium dioxide results in decreased expression of GPC2 mRNAPMID:29264374
Gpc2decreases methylationISOGpc2 (Mus musculus)6480464CTDtitanium dioxide results in decreased methylation of GPC2 promoter alternative formPMID:35295148
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