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GENE - TERM ANNOTATION REPORT

RGD ID: 621256
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lin7a
Name: lin-7 homolog A, crumbs cell polarity complex component
Acc ID: GO:0045202
Term: synapse
Definition: The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
Definition Source(s): GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lin7ais_active_inIBAFB:FBgn0039269 or MGI:1330839 or PANTHER:PTN000362448 or Lin7b (Rattus norvegicus) or Lin7c (Rattus norvegicus) or Lin7a (Rattus norvegicus)1600115GO_CentralGO_REF:0000033

GO_REF:0000033
Lin7ais_active_inIDA 11041013SynGOPMID:10341223

 
Lin7ais_active_inIEP 11041013SynGOPMID:10341223

 
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