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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
cell junction +     
anchoring junction +   
flagella connector 
synapse +   
The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.

Synonyms
Exact Synonyms: synaptic junction
Narrow Synonyms: mixed synapse
Related Synonyms: electrotonic synapse
Xrefs: NIF_Subcellular:sao914572699 ;   Wikipedia:Chemical_synapse
Only In Taxon: NCBITaxon:33208 ! Metazoa
Definition Sources: GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.