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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621146
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hyou1
Name: hypoxia up-regulated 1
Acc ID: CHEBI:59219
Term: ceruletide
Definition: A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction.
Chemical ID: MESH:D002108
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hyou1increases expressionEXP 6480464CTDCeruletide results in increased expression of HYOU1 proteinPMID:18024178
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