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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621146
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hyou1
Name: hypoxia up-regulated 1
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hyou1decreases expressionISOHYOU1 (Homo sapiens)6480464CTDOzone results in decreased expression of HYOU1 mRNAPMID:23033980
Hyou1multiple interactionsISOHYOU1 (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of HYOU1 mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of HYOU1 mRNA; [Volatile Organic Compounds co-treated with Ozone] results in increased oxidation of HYOU1 mRNAPMID:32699268
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