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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62109
Species: Mus musculus
RGD Object: Gene
Symbol: Col1a1
Name: collagen, type I, alpha 1
Acc ID: CHEBI:8633
Term: puerarin
Definition: A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 7 and 4' and a beta-D-glucopyranosyl residue at position 8 via a C-glycosidic linkage.
Chemical ID: MESH:C033607
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1multiple interactionsEXP 6480464CTDpuerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of COL1A1 mRNA]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]PMID:27318789 PMID:31273855
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