GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgm2 | increases activity | ISO | TGM2 (Homo sapiens) | 6480464 | CTD | Alitretinoin results in increased activity of TGM2 protein | PMID:9516142 | Tgm2 | increases expression | ISO | TGM2 (Homo sapiens) | 6480464 | CTD | Alitretinoin results in increased expression of TGM2 mRNA; Alitretinoin results in increased expression of TGM2 protein | PMID:15964820 PMID:16158052 PMID:17034753 PMID:9516142 | Tgm2 | multiple interactions | ISO | TGM2 (Homo sapiens) | 6480464 | CTD | [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4C16 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 protein]; periodate-oxidized adenosine inhibits the reaction [Alitretinoin results in increased expression of TGM2 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]]; Vitamin D promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA] | PMID:15964820 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |