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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgm2
Name: transglutaminase 2
Acc ID: CHEBI:28157
Term: pinocembrin
Definition: A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea.
Chemical ID: MESH:C016063
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgm2multiple interactionsISOTGM2 (Homo sapiens)6480464CTDpinocembrin inhibits the reaction [Ethanol results in increased activity of TGM2 protein]; pinocembrin inhibits the reaction [Ethanol results in increased expression of TGM2 mRNA]PMID:18295389
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