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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621074
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sfrp1
Name: secreted frizzled-related protein 1
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sfrp1decreases expressionEXP 6480464CTDGlyphosate results in decreased expression of SFRP1 mRNAPMID:26302742
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