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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621042
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pik3r3
Name: phosphoinositide-3-kinase regulatory subunit 3
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pik3r3decreases expressionISOPIK3R3 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of PIK3R3 mRNAPMID:20886546 PMID:38568856
Pik3r3multiple interactionsISOPIK3R3 (Homo sapiens)6480464CTD[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of PIK3R3 mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PIK3R3 mRNAPMID:39836092
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