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GENE - TERM ANNOTATION REPORT

RGD ID: 621008
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abi1
Name: abl-interactor 1
Acc ID: GO:0031209
Term: SCAR complex
Definition: A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.
Definition Source(s): GOC:hla, GOC:pg, PMID:12181570, PMID:24036345, PMID:24630101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abi1part_ofISOABI1 (Homo sapiens)1624291RGD PMID:21107423 PMID:26428302

PMID:21107423 PMID:26428302
Abi1part_ofISOAbi1 (Mus musculus)1624291RGD PMID:12672821 PMID:26428302

PMID:12672821 PMID:26428302
Abi1part_ofIEAUniProtKB:Q8CBW3 or ensembl:ENSMUSP000001184911600115EnsemblGO_REF:0000107

GO_REF:0000107
Abi1part_ofIEAUniProtKB:Q8IZP0 or ensembl:ENSP000003653101600115EnsemblGO_REF:0000107

GO_REF:0000107
Abi1part_ofIBAFB:FBgn0020510 or MGI:104913 or MGI:1913860 or PANTHER:PTN000048906 or UniProtKB:Q8IZP0 or UniProtKB:Q9NYB9 or UniProtKB:Q9P2A4 or dictyBase:DDB_G02679561600115GO_CentralGO_REF:0000033

GO_REF:0000033
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