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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620967
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map3k2
Name: mitogen activated protein kinase kinase kinase 2
Acc ID: CHEBI:63623
Term: succimer
Definition: A sulfur-containing carboxylic acid that is succinic acid bearing two mercapto substituents at positions 2 and 3. A lead chelator used as an antedote to lead poisoning.
Chemical ID: MESH:D004113
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k2multiple interactionsISOMAP3K2 (Homo sapiens)6480464CTD[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of MAP3K2 mRNAPMID:26378955
Map3k2multiple interactionsISOMap3k2 (Mus musculus)6480464CTD[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of MAP3K2 mRNAPMID:26378955
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