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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620963
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eif2s1
Name: eukaryotic translation initiation factor 2 subunit alpha
Acc ID: CHEBI:60312
Term: 2-amino-2-deoxy-D-galactopyranose
Definition: The pyranose form of D-galactosamine.
Chemical ID: MESH:D005688
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif2s1multiple interactionsEXP 6480464CTD4-phenylbutyric acid affects the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of EIF2S1 mRNA]; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of and results in decreased phosphorylation of EIF2S1 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of EIF2S1 mRNAPMID:28844859
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