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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620925
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppargc1a
Name: PPARG coactivator 1 alpha
Acc ID: CHEBI:2719
Term: Ile(5)-angiotensin II
Definition: An angiotensin II that acts on the central nervous system (PDB entry: 1N9V).
Chemical ID: MESH:D000804
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1adecreases expressionEXP 6480464CTDAngiotensin II results in decreased expression of PPARGC1A proteinPMID:37269933
Ppargc1amultiple interactionsEXP 6480464CTDcelastrol methyl ester inhibits the reaction [Angiotensin II results in decreased expression of PPARGC1A protein]PMID:37269933
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