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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620893
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkaa2
Name: protein kinase AMP-activated catalytic subunit alpha 2
Acc ID: CHEBI:139388
Term: 1,3,7,9-tetramethyluric acid
Definition: An oxopurine that is uric acid in which the hydrogens at positions 1,3,7 and 9 are replaced by methyl groups. It is a purine alkaloid that is found in Chinese tea known as kucha (Camellia assamica var. kucha) and exhibits anti-inflammatory and analgesic properties.
Chemical ID: MESH:C077059
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkaa2multiple interactionsEXP 6480464CTD1,3,7,9-tetramethyluric acid inhibits the reaction [[Dietary Fats co-treated with Ethanol co-treated with Carbon Tetrachloride] results in decreased phosphorylation of PRKAA2 protein]PMID:35872049
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