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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620722
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zfp36
Name: zinc finger protein 36
Acc ID: CHEBI:17594
Term: hydroquinone
Definition: A benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Chemical ID: MESH:C031927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zfp36decreases expressionISOZFP36 (Homo sapiens)6480464CTDhydroquinone results in decreased expression of ZFP36 proteinPMID:23288922 PMID:35302183
Zfp36multiple interactionsISOZFP36 (Homo sapiens)6480464CTDbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein]; ZFP36 protein inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]; ZFP36 protein inhibits the reaction [hydroquinone results in increased expression of TNF protein]PMID:23288922 PMID:35302183
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