GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Zfp36 | increases expression | ISO | Zfp36 (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of ZFP36 mRNA; Lipopolysaccharides results in increased expression of ZFP36 protein | PMID:10975854 PMID:15710351 PMID:18032482 PMID:24095726 | Zfp36 | multiple interactions | ISO | ZFP36 (Homo sapiens) | 6480464 | CTD | [Nicotine co-treated with Lipopolysaccharides] results in increased expression of ZFP36 mRNA; [Nicotine co-treated with Lipopolysaccharides] results in increased expression of ZFP36 protein; Bungarotoxins inhibits the reaction [[Nicotine co-treated with Lipopolysaccharides] results in increased expression of ZFP36 mRNA]; methyllycaconitine inhibits the reaction [[Nicotine co-treated with Lipopolysaccharides] results in increased expression of ZFP36 mRNA]; ZFP36 mRNA affects the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]] | PMID:21606497 | Zfp36 | multiple interactions | ISO | Zfp36 (Mus musculus) | 6480464 | CTD | [Lipopolysaccharides co-treated with Nicotine] results in increased expression of ZFP36 mRNA; apicidin inhibits the reaction [RU24858 inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]]; CGP 57380 inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 protein]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 protein]; HMOX1 protein promotes the reaction [[Lipopolysaccharides co-treated with Nicotine] results in increased expression of ZFP36 mRNA]; HMOX1 protein promotes the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]; HMOX1 protein promotes the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]]; IRAK2 protein promotes the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein results in decreased degradation of ZFP36 protein]]; Lipopolysaccharides promotes the reaction [[ZFP36 protein binds to YWHAQ protein] which results in decreased degradation of TNF mRNA]; Lipopolysaccharides promotes the reaction [TLR4 protein results in decreased degradation of ZFP36 protein]; Lipopolysaccharides promotes the reaction [ZFP36 protein binds to YWHAQ protein]; Lipopolysaccharides results in increased expression of and results in increased phosphorylation of ZFP36 protein; Mifepristone inhibits the reaction [RU24858 inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]]; RU24858 inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]; RU24858 inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 protein]; STAT3 protein promotes the reaction [[Lipopolysaccharides co-treated with Nicotine] results in increased expression of ZFP36 mRNA]; STAT3 protein promotes the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]; trichostatin A inhibits the reaction [RU24858 inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]]; ZFP36 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; ZFP36 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; ZFP36 protein promotes the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; ZFP36 protein promotes the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; zinc protoporphyrin inhibits the reaction [[Nicotine co-treated with Lipopolysaccharides] results in increased expression of ZFP36 mRNA] | PMID:15014438 PMID:15710351 PMID:18032482 PMID:21291324 PMID:22093924 PMID:24095726 | | ||||||||||||||||||||||
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