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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620597
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plaur
Name: plasminogen activator, urokinase receptor
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plaurincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PLAUR mRNAPMID:33387578
Plauraffects expressionISOPlaur (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PLAUR mRNAPMID:21570461
Plaurdecreases expressionISOPlaur (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PLAUR mRNAPMID:19684285 PMID:19933214
Plaurdecreases expressionISOPLAUR (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PLAUR mRNAPMID:19619570
Plaurincreases expressionISOPlaur (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PLAUR mRNAPMID:22666406
Plaurincreases expressionISOPLAUR (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of PLAUR mRNAPMID:19684285
Plaurmultiple interactionsISOPlaur (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PLAUR mRNAPMID:17942748
Plaurmultiple interactionsISOPLAUR (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PLAUR mRNAPMID:19619570
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