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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620596
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccr5
Name: C-C motif chemokine receptor 5
Acc ID: CHEBI:15551
Term: prostaglandin E2
Definition: Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.
Chemical ID: MESH:D015232
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccr5decreases expressionISOCCR5 (Homo sapiens)6480464CTDDinoprostone results in decreased expression of CCR5 mRNA; Dinoprostone results in decreased expression of CCR5 proteinPMID:16303787
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