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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620436
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cga
Name: glycoprotein hormones, alpha polypeptide
Acc ID: CHEBI:6842
Term: methoxychlor
Definition: An organochlorine insecticide that has formula C16H15Cl3O2.
Chemical ID: MESH:D008731
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cgaincreases expressionISOCga (Mus musculus)6480464CTDMethoxychlor results in increased expression of CGA mRNAPMID:24814263
Cgamultiple interactionsISOCGA (Homo sapiens)6480464CTDMethoxychlor affects the reaction [CGA protein results in increased expression of AR mRNA]PMID:27391359
Cgamultiple interactionsISOCga (Mus musculus)6480464CTD2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Methoxychlor results in increased expression of CGA mRNA]PMID:24814263
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