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GENE - TERM ANNOTATION REPORT

RGD ID: 620430
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myoc
Name: myocilin
Acc ID: DOID:9282
Term: ocular hypertension
Definition: An eye disease that is characterized by elevated intraocular pressure in the absence of optic nerve damage or visual field loss. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Ocular_hypertension "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myoc IEP 1601004RGDmRNA:increased expression:retina (rat) 
Myoc ISOMyoc (Mus musculus)7394804RGDmRNA:decreased expression:eye, trabecular mesh (mouse) 
Myoc ISOMYOC (Homo sapiens)7394831RGDassociated with Glaucoma, Primary Open Angle; DNA:snp:cds:p.T377M (human) 
MyoctreatmentISOMyoc (Mus musculus)7394804RGD  
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