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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620190
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Becn1
Name: beclin 1
Acc ID: CHEBI:10106
Term: zearalenone
Definition: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.
Chemical ID: MESH:D015025
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Becn1increases expressionEXP 6480464CTDZearalenone results in increased expression of BECN1; Zearalenone results in increased expression of BECN1 proteinPMID:24530352 PMID:32858132
Becn1increases expressionISOBecn1 (Mus musculus)6480464CTDZearalenone results in increased expression of BECN1 proteinPMID:31982503
Becn1multiple interactionsISOBecn1 (Mus musculus)6480464CTDacadesine promotes the reaction [Zearalenone results in increased expression of BECN1 protein]PMID:31982503
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