Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	620160
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Bid
Name:	BH3 interacting domain death agonist

Acc ID:	CHEBI:22689
Term:	bafilomycin A1
Definition:	The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus.
Chemical ID:	MESH:C040929

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Bid	increases expression	EXP		6480464	CTD	bafilomycin A1 results in increased expression of BID protein modified form	PMID:28378122
Bid	multiple interactions	EXP		6480464	CTD	bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]	PMID:28378122
Bid	increases cleavage	ISO	BID (Homo sapiens)	6480464	CTD	bafilomycin A1 results in increased cleavage of BID protein	PMID:26853465
Bid	multiple interactions	ISO	BID (Homo sapiens)	6480464	CTD	vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of BID protein]	PMID:26853465

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