Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	620158
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Smad5
Name:	SMAD family member 5

Acc ID:	CHEBI:16469
Term:	17beta-estradiol
Definition:	The 17beta-isomer of estradiol.
Chemical ID:	MESH:D004958

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Smad5	increases expression	ISO	Smad5 (Mus musculus)	6480464	CTD	Estradiol results in increased expression of SMAD5 mRNA	PMID:25210133

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.