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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620135
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ap2m1
Name: adaptor related protein complex 2 subunit mu 1
Acc ID: CHEBI:40909
Term: azoxystrobin
Definition: An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture.
Chemical ID: MESH:C087670
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ap2m1decreases expressionISOAP2M1 (Homo sapiens)6480464CTDazoxystrobin results in decreased expression of AP2M1 mRNAPMID:33512557
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