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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620066
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Paics
Name: phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Paicsincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PAICS mRNAPMID:16960034
Paicsincreases expressionISOPAICS (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of PAICS mRNAPMID:19684285
Paicsincreases expressionISOPaics (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PAICS mRNAPMID:15328365 PMID:16960034
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