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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620023
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chrm2
Name: cholinergic receptor, muscarinic 2
Acc ID: CHEBI:34714
Term: dimethoate
Definition: A monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group.
Chemical ID: MESH:D004117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrm2decreases expressionEXP 6480464CTDDimethoate results in decreased expression of CHRM2 mRNA; Dimethoate results in decreased expression of CHRM2 proteinPMID:14694657 PMID:15033006
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