GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | increases expression | EXP | | 6480464 | CTD | Sildenafil Citrate results in increased expression of VEGFA mRNA; Sildenafil Citrate results in increased expression of VEGFA protein | PMID:18373738 PMID:20583517 | Vegfa | multiple interactions | EXP | | 6480464 | CTD | Sildenafil Citrate inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of VEGFA protein]; Sildenafil Citrate inhibits the reaction [Aflatoxin B1 results in increased expression of VEGFA mRNA]; Sildenafil Citrate inhibits the reaction [alpha-naphthyl thiourea results in increased expression of VEGFA mRNA]; Sildenafil Citrate inhibits the reaction [alpha-naphthyl thiourea results in increased expression of VEGFA protein] | PMID:30974023 PMID:32959702 PMID:35608386 | |
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