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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619881
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Neu3
Name: neuraminidase 3
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Neu3decreases expressionISONeu3 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of NEU3 mRNAPMID:19770486
Neu3decreases methylationISONEU3 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of NEU3 promoterPMID:27901495
Neu3increases expressionISONEU3 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of NEU3 mRNAPMID:20498004
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