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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619830
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd40
Name: CD40 molecule
Acc ID: CHEBI:84491
Term: poly(I:C)
Definition: A mismatched double-stranded RNA with one strand being a polymer of inosinic acid, the other a polymer of cytidylic acid.
Chemical ID: MESH:D011070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd40increases expressionISOCD40 (Homo sapiens)6480464CTDPoly I-C results in increased expression of CD40 proteinPMID:15246609
Cd40multiple interactionsISOCD40 (Homo sapiens)6480464CTD[Poly I-C co-treated with IFNG protein] results in increased secretion of CD40 protein; [TL8-506 co-treated with Poly I-C] results in increased expression of CD40 mRNAPMID:16224278 PMID:35688559
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