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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619785
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ap1g1
Name: adaptor related protein complex 1 subunit gamma 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ap1g1decreases methylationISOAP1G1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of AP1G1 promoterPMID:27901495
Ap1g1increases expressionISOAp1g1 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of AP1G1 mRNAPMID:22228805
Ap1g1increases methylationISOAP1G1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of AP1G1 3' UTRPMID:27901495
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